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  • Name: DMBX-A,GTS-21
  • * CAS #: 156223-05-1
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Product name : gts-21(dmxb-a) 
Cas No.:  156223-05-1 

Chemical name : GTS-21 dihydrochloride;  DMXB-A

MF: C19H20N2O2 
MW:  308.374

Appearance:white powder


GTS-21 (DMBX-A) is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent.
Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21[3] display nootropic[4] and neuroprotective effects, andGTS-21 is being investigated for the treatment of Alzheimer's disease,[9] nicotine dependence,[10] and, most significantly, for schizophrenia.